Careers

At C4X, we believe in doing drug discovery better. To do this, we have created two of the best cutting-edge technologies and combined them into a drug discovery powerhouse. We are using our engine to identify the best targets and rationally design the best drug molecules. Daily we are demonstrating that our approach is more reliable, more productive, more efficient and much much more rewarding.

Are you tired of conventional drug discovery approaches? Tired of not being empowered to make a difference? Tired of bureaucracy? Then come and be part of something different - come and join our agile multi-disciplinary team and build a pipeline to be proud of.

If you have caught the excitement of our vision and want to work in a place of momentum and opportunity then C4X could be the right place for you.

If you are interested in working at C4X, please enquire at jobs@c4xdiscovery.com about any of the roles listed below:

Computational Biologists/Statistical Geneticists

We are looking for data scientists with experience in Computational Biology and/or Statistical Genetics to lead the application of novel mathematics (Taxonomy3®) to big genetic datasets. You will be responsible for generating novel genetic insights with the aim of identifying novel drug targets in complex disorders.

The roles are based in C4X Discovery’s new central London facility. To succeed in this position, you will need a degree (or equivalent) in Genetics, Bioinformatics or Statistics and experience in mining big genetic datasets, together with a high level of self-motivation, flexibility and organisational skills.

Computational Chemists

At C4X we are building an exciting drug discovery portfolio by bringing together experimentally determined small molecule NMR solution conformational data, X-ray crystallographic data, small molecule modelling and structure-based drug design. If you are interested in this and keen to explore opportunities to create, build and integrate new tools to explore conformational data more fully in the computational chemistry workflow and drug design process join us at C4X. Projects will be focused on delivering multiple pre-clinical candidates spanning different therapeutic areas, making this a diverse, fast-moving and challenging opportunity for the right applicants.

IT Manager

C4X Discovery are looking to recruit an IT Manager for its head office in Manchester.

As an IT Manager you will be responsible for overseeing the delivery of IT services and support for the company. You will work with the Technology Strategist to draw up IT strategy and implement IT solutions suitable to the company’s needs.

Lead Unreal Engine Programmer

We are actively building a team of programmers to work on this exciting project bringing game engine visualisation to the corporate world of Drug Discovery. We will be using the Unreal Engine with 3rd party and proprietary tools to produce cutting edge systems to visualise molecules in 3D and VR.

We are therefore looking for an experienced lead programmer who can oversee the project from design and architecture through to completion.

Medicinal Chemists

C4X Discovery is currently looking to extend its team of drug hunters with talented, highly motivated medicinal chemists with industry experience to grow the teams located in Manchester and London. You will lead the scientific direction of one or more drug discovery projects and will be responsible for the design of innovative chemical series. You will also have the unique opportunity to generate novel insights into the conformational behavior of molecules and the underlying guiding principles of conformational control. Projects will be focused on delivering multiple pre-clinical candidates spanning different therapeutic areas, making this a diverse, fast-moving and challenging opportunity for the right applicants.

NMR Spectroscopists

We are looking for talented researchers who have recently acquired a PhD in solution-state NMR. This is an exciting opportunity for scientists with an analytical mind and a high level of problem-solving skills and the capability to work in small, multidisciplinary teams. You will use the company’s proprietary “Conformetrix” technology to determine the solution conformational behaviour of molecules from NMR data and apply the learning from these data to understand and manipulate the drivers of molecular conformation. These analyses underpin the design of novel drug candidates in the C4X Discovery engine.

Senior ADME Scientists

We are actively recruiting scientists with experience of Drug Metabolism and Pharmacokinetics and a background in drug discovery. The successful candidates will work in an office-based environment as part of multiple project teams to define the ADME strategy, project manage DMPK testing of compounds both in vitro and in vivo conducted by our outsourcing partners and lead data interpretation activities. Projects will be focused on delivering multiple pre-clinical candidates spanning different therapeutic areas, making this a diverse, fast-moving and challenging opportunity for the right applicants.

Senior Bioscientists

We are actively recruiting experienced bioscientists with a demonstrable record of innovative science in drug discovery for an office-based role. The successful candidates will evaluate new targets to add to our pipeline and work as part of multiple project teams to establish and manage the screening cascades for testing compounds both in vitro and in vivo conducted by our outsourcing partners. Projects will be focused on delivering multiple pre-clinical candidates spanning different therapeutic areas, making this a diverse, fast-moving and challenging opportunity for the right applicants.