Research Collaborations
Driving our technology into the future

The Conformetrix technology platform measures the preferred shapes of molecules in solution using NMR data, and this new information underpins our productivity in developing new drugs. We are committed to researching ways to determine molecular shapes ever more precisely while seeking new applications for our molecular shapes in drug development. Some of our research collaboration partners and projects are described here.

University of Bristol

Dr Craig Butts
With Dr Craig Butts at the University of Bristol, we are developing NMR methods for measuring and interpreting carbon-hydrogen coupling data to determine molecular shapes with enhanced precision.

University of Reading

Dr Kenneth Shankland
With Dr Kenneth Shankland at the University of Reading, we are applying NMR and conformational data to enhance crystal structure determination by X-ray powder diffraction.

University of Oxford

Dr Wes Armour
With Dr Wes Armor at the Oxford e-Research Centre we are improving the efficiency of our Taxonomy3® software by implementing GPU's parallel computing power to rapidly analyse very large genetic datasets.

University of Manchester

Prof Tony Day
With Prof Tony Day at the Faculty of Life Sciences of the University of Manchester, we are combining protein NMR methods synergistically with our ligand-based NMR technology to pioneer new workflows in conformational design, using glycosaminoglycan-protein interactions as an exemplar system.

University of Manchester

Prof Roger Davy & Dr Aurora Cruz-Cabeza
With Prof Roger Davy and Dr Aurora Cruz-Cabeza at the School of Chemical Engineering and Analytical Science of the University of Manchester, we are investigating how preferred solution shapes can be used to predict, understand and control drug polymorphism and crystal nucleation.

University of Manchester

Dr Elena Bichenkova
With Dr Elena Bichenkova at the Manchester Pharmacy School of the University of Manchester we are using our technology to understand the fundamental mechanisms underlying the action of chemical ribonucleases, a particular class of enzyme mimics that can be fabricated in the laboratory by chemical fusion of two inactive precursors to produce a novel, biologically active chimeric molecule capable of recognising and cleaving physiologically significant RNA.