C4X Discovery is guided by a Board with extensive expertise in drug discovery and development, clinical trials, transactions and fundraising. The team is detailed below.
Sam has 20 years' experience in the biotechnology industry, both as a top-ranked equity analyst in the City and, subsequently, as an entrepreneur and chief executive. He is CEO of Istesso Ltd, a London-based drug discovery company, a Non-Executive Director of Diurnal Group plc and Chairman of Glythera Ltd. He holds a PhD in molecular biology from Cambridge and a degree in biology from Oxford.
Clive has more than 30 years’ experience in life science research, with over 20 years in senior pharmaceutical industry positions and a degree and PhD in Pharmacology. His expertise includes an in-depth understanding of all facets of drug discovery and development, a broad knowledge of the science and commercial landscape of a variety of therapeutic areas and solid experience of the pharmaceutical business and finance community supporting the sector.
Clive was co-founder and chief executive of Convergence Pharmaceuticals Ltd, which was acquired by Biogen in January 2015.
Clive was previously co-founder and chief executive of PowderMed Ltd, a vaccines development company acquired by Pfizer in November 2006. Before that he was senior vice president, research and development and a Board member of PowderJect Pharmaceuticals plc until its acquisition by Chiron Vaccines in 2003. Clive began his career in industry at Ciba-Geigy and then GlaxoWellcome, where he left as UK research director in 2001. Clive is a recent past chairman of the BioIndustry Association, is currently non-executive chairman of Touchlight Genetics Ltd and Centauri Ltd, and is a non-executive member of the Medicines Discovery Catapult Board, and a non-executive director of Carrick Therapeutics.
Craig is an experienced biologist having worked on and managed many drug discovery and development projects during the last 18 years, from initial target selection right through to investigating clinical efficacy and safety in Phase 2 patient studies. Craig joined C4X as Head of Biology in June 2015 before becoming Chief Scientific Officer in October later that year. Prior to joining C4XD, Craig was director of respiratory research at Pulmagen Therapeutics, a clinical stage company spun-out of Argenta in 2010. At Pulmagen, Craig managed several of its collaborations and partnerships, including those with AstraZeneca, Chiesi, Domantis, Dr Reddy’s, Skyepharma and Teijin Pharma. Craig was part of the Etiologics Team that merged with Argenta Discovery in 2004 and prior to this he worked for Bayer as a research scientist. Craig has a PhD in Respiratory Medicine from Birmingham University and a first-class biochemistry degree from the University of Surrey.
Brad has more than 20 years’ experience in the pharmaceutical and biotechnology industries and has held a number of senior financial and general management positions in both the UK and the US. Previously, Brad was chief financial officer of Plethora Solutions Holdings plc, an AIM-listed specialty pharmaceutical company, chief executive officer of Xcellsyz Limited, a UK venture capital-backed life science company, and senior director of Geron Corporation’s stem cell-focussed UK subsidiary. Brad is a co-founder of Seven Hills Venture Partners, a life sciences advisory firm, and previously served as non-executive director on the board of directors for e-Therapeutics plc for nine years.
Harry has significant experience within the pharmaceutical industry, specialising in medicinal chemistry, drug discovery and development. Currently he is an independent consultant working with a variety of small biotech companies and investors, many of which are in the oncology arena. Harry is also a non-executive director of Pulmocide Therapeutics and Artios Pharma Ltd. After attaining a PhD in Organic Chemistry, Harry worked at Ciba-Geigy AG (Now Novartis AG) and Roche Allen & Hanburys Limited, before joining GlaxoWellcome plc where he became director of Chemistry. Harry is an expert in the respiratory area of the pharma industry and is co-inventor of GSK’s successful asthma drug salmeterol (Serevent). In addition, he has worked across a range of therapeutic areas and at several biotechnology companies, including Ribotargets, Vernalis, Argenta and Pulmagen.
Alex has a proven track record in identifying, investing and growing businesses within the pharmaceutical sector. He is currently Chief Scientific Officer at 4D pharma plc.
From 2008, Alex was a director and shareholder of Aquarius Equity Partners Limited, and he joined the Board of C4XD as a Non-Executive Director following Aquarius’ investment in the Company. Prior to this, Alex worked for IP Group plc where he specialised in life science investments.
Alex has been involved in a number of private and public companies, including Nanoco Group plc, admitted to AIM in 2009; Retroscreen Virology Group plc, admitted to AIM in 2012; Tissue Regenix Group plc, admitted to AIM in 2010; and Auralis Limited, which, after investment through Aquarius Equity Partners Limited, delivered a seven-fold return through to its trade sale to ViroPharma Inc in 2010.