Media

THIS ANNOUNCEMENT CONTAINS INSIDE INFORMATION FOR THE PURPOSES OF ARTICLE 7 OF REGULATION 2014/596/EU.

C4X Discovery Holdings plc

(“C4XD”, “C4X Discovery” or the “Company”)

Interim results for the six months ended 31 January 2018

12 April 2018 - C4X Discovery Holdings plc (AIM: C4XD), a pioneering drug discovery company, today announces its interim results for the six months ended 31 January 2018.

C4X Discovery Holdings plc

("C4XD" or the "Company")

C4X Discovery signs licensing agreement with Indivior for addiction programme worth up to $294m

C4XD receives $10 million upfront, potential milestones totalling $284 million plus royalties

29 March 2018 – C4X Discovery Holdings plc (AIM: C4XD), a pioneering drug discovery company, today announces that it has signed a licensing agreement with Indivior UK Limited (LON: INDV, "Indivior") to further develop and commercialise C4XD’s oral Orexin-1 receptor antagonist ("C4X3256") for the treatment of addiction. C4X3256 aims to treat addiction by targeting the "craving" process itself and, therefore, can be applied across a broad range of substance use disorders. The treatment of addiction represents a substantial area of unmet medical need, forecast to be worth an estimated $13 billion per annum in 20181.

C4X Discovery Holdings plc

("C4XD" or the "Company")

Full year results for the year ended 31 July 2017

14 December 2017 – C4X Discovery Holdings plc (AIM: C4XD), a pioneering drug discovery company, today announces its full year results for the year ended 31 July 2017.

C4X Discovery Holdings plc

(“C4XD”, “C4X Discovery” or the “Company”)

C4XD presents data on its lead addiction programme: Orexin-1 antagonist

Programme demonstrates potential application across a broad range of substance use disorders

13 November 2017 – C4X Discovery Holdings plc (AIM: C4XD), a pioneering drug discovery company, presented new pre-clinical data on its Orexin-1 antagonist programme at Neuroscience 2017 on 11th November 2017 in Washington, DC.

Tuesday, 05 September 2017

Business Update

C4X Discovery Holdings plc

(“C4XD”, “C4X Discovery” or the “Company”)

Business Update

5 September 2017 - C4X Discovery Holdings plc (AIM: C4XD), a pioneering drug discovery company, today provides an update on the Drug Discovery Engine and portfolio progress.

THIS ANNOUNCEMENT CONTAINS INSIDE INFORMATION FOR THE PURPOSES OF ARTICLE 7 OF REGULATION 2014/596/EU.

C4X Discovery Holdings plc

(“C4XD”, “C4X Discovery” or the “Company”)

Interim results for the six months ended 31 January 2017

27 April 2017 - C4X Discovery Holdings plc (AIM: C4XD), a pioneering drug discovery company, today announces its interim results for the six months ended 31 January 2017.

C4X Discovery Holdings plc
(“C4XD” or the “Company”)

Result of General Meeting
and
Issue of Equity

31 March 2017 – C4X Discovery Holdings plc (AIM: C4XD), a pioneering drug discovery company, today announces that, at the General Meeting held earlier today in respect of its £7.0m Placing at a Placing Price of 85 pence per new Ordinary Share, which was announced to the market on 14 March 2017, all the resolutions put to shareholders were duly passed.

C4X Discovery Holdings plc

("C4XD", "C4X Discovery" or the "Company")

Results of Placing

1.30 p.m. GMT, 14 March 2017 - C4X Discovery Holdings plc (AIM: C4XD), a pioneering drug discovery company, is pleased to announce the completion of the Placing announced earlier today.

A total of 8,235,294 Placing Shares have been placed by Panmure Gordon (UK) Limited at a Placing Price of 85 pence per new Ordinary Share to raise a total of approximately £7.0 million for the Company (before expenses). The Placing Shares being issued represent approximately 22.0 per cent. of the issued ordinary share capital of the Company prior to the Placing. The Placing Price represents a discount of 7.1 per cent. to the Company's mid-market closing price as at 13 March 2017, being the last practicable day before the announcement of the Placing.

The net proceeds of the Placing receivable by the Company will be used to support the execution of its strategy of becoming the world's most productive, self-sustaining drug discovery engine by strengthening its balance sheet as partnering discussions and strategic collaborations progress, expanding its commercial capability and supporting working capital during the expansion of its pipeline portfolio.