Expansion of Team with Strong Biology and Development Expertise

3 September, 2015 – C4X Discovery Holdings plc (“C4XD” or “the Company”), a leader in rational drug discovery and design, today announced that it is further strengthening its team with two new management appointments.

Dr Craig Fox joins the Company as Head of Biology and a member of the Senior Management Team. Dr Fox is an experienced biologist having worked on and managed many drug discovery and development projects during the last 18 years, from initial target selection right through to investigating clinical efficacy and safety in Phase II patient studies. Prior to joining C4XD, Dr Fox was Director of Respiratory Research at Pulmagen Therapeutics, a clinical stage company spun-out of Argenta in 2010. Dr Fox also managed several of Pulmagen’s collaborations and partnerships, including those with AstraZeneca, Chiesi, Domantis, Dr Reddy’s, Skyepharma and Teijin Pharma. Dr Fox was part of the Etiologics Team that merged with Argenta Discovery in 2004 and prior to this he worked for Bayer as a Research Scientist.

Dr Clare Murray joins the Company as Project Manager. Dr Murray spent 23 years with AstraZeneca, where she was most recently Associate Director, Bioscience, within the Emerging Innovations Unit. Whilst at AstraZeneca, Dr Murray led biology, pharmacology and clinical development teams up to Phase II across a range of therapeutic areas including respiratory, inflammation, dermatitis and oncology. Dr Murray has spent the last year at the University of Manchester’s Faculty of Medical and Human Sciences with responsibility for managing a portfolio of translational research projects.

“We are delighted to have further strengthened our management team with the addition of these two highly experienced development professionals and qualified biologists,” said Piers Morgan, CEO of C4XD. “Craig and Clare are highly respected, with solid track records of successfully progressing programmes into early stage clinical development in man, and bring a wealth of deep and relevant experience to support the continued development and value enhancement of our pipeline of programmes.”